To discharge the duties of an office; to take charge of business; to manage affairs; to serve in the conduct of affairs, in the application of things to their uses; to settle and distribute the estate of a decedent. In physiology, and in criminal law, to administer means to cause or procure a person to take some drug or other substance into his or her system; to direct and cause a medicine, poison, or drug to be taken into the system. State v. Jones, 4 Pennewill (Del.) 109, 53 Atl. 801; McCaugliey v. State, 150 I lid. 41, 59 N. E. 109; La Beau v. People, 34 N. Y. 223; Sumpter v. State, 11 Fla. 247; Robbins v. State, 8 Ohio St 131.